Which factor does NOT contribute to venous disease?

Hyperthyroidism does not directly contribute to venous disease. Venous diseases are typically related to factors that impact the veins' ability to function properly, which involves issues such as blood flow, clotting, and inflammation within the venous system.

Deep vein thrombosis (DVT) is a significant contributor to venous disease, as it refers to blood clots that form in the deep veins, particularly in the legs, which can lead to complications such as chronic venous insufficiency or pulmonary embolism.

Lupus, an autoimmune disease, can also exacerbate venous disease through inflammation and clotting disorders associated with the condition.

Vitamin C deficiency, while more commonly linked to conditions like scurvy, can also impact overall wound healing and the integrity of the vascular system.

In contrast, hyperthyroidism primarily affects the metabolism and may lead to various systemic issues, but it is not recognized as a direct factor influencing the development of venous disease. Thus, it's accurate to identify it as the option that does not contribute to venous disease.