Which class of medication includes gabapentin and pregabalin for the treatment of neuropathic pain?

Gabapentin and pregabalin belong to the class of medications known as antiepileptics, which are primarily used to treat seizures. However, they have also been found to be effective in managing neuropathic pain. Both medications work by modulating the release of excitatory neurotransmitters, ultimately helping to reduce the perception of pain.

Their effectiveness for neuropathic pain has led to their widespread use not only in seizure management but also in conditions such as diabetic neuropathy, postherpetic neuralgia, and other pain syndromes. This represents an important aspect of their pharmacological profile, underscoring their dual utility beyond just anti-seizure activity.

The other classes mentioned do not include gabapentin and pregabalin. Opioids are primarily used for chronic pain management but do not work on neuropathic pain as effectively. Non-steroidal anti-inflammatory drugs target inflammation and typically do not address neuropathic pain mechanisms. Muscle relaxants are used to relieve muscle spasms and discomfort but do not provide the specific action required for neuropathic pain relief. Hence, identifying gabapentin and pregabalin as antiepileptics is essential for understanding their role in neuropathic pain management.